What's in your (con) wallet?
A while back, Penny Arcade's Robert Khoo suggested a terrific rule-of-thumb for estimating the amount of change you'll need at a comic convention. In a nutshell, it suggested bringing 4-5% of your projected sales in ones and fives.
Of course, if the bank you use doesn't have a branch in the town the convention is in, this can be tricky. And even if it does, it's just one more thing to try to figure out in a strange city.